Physical Properties | | | |
Molecular Weight: 490.964 g/mol | logS: -6.53124 | SlogP: 3.54402 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0237632 | Sterimol/B1: 2.21779 | Sterimol/B2: 3.72717 | Sterimol/B3: 4.42611 |
Sterimol/B4: 7.60482 | Sterimol/L: 22.453 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 737.086 | Positive charged surface: 402.996 | Negative charged surface: 334.09 | Volume: 425.875 |
Hydrophobic surface: 550.174 | Hydrophilic surface: 186.912 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |