Physical Properties | | | |
Molecular Weight: 403.448 g/mol | logS: -4.58422 | SlogP: 4.75772 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0273794 | Sterimol/B1: 2.16658 | Sterimol/B2: 3.45499 | Sterimol/B3: 3.76522 |
Sterimol/B4: 8.00206 | Sterimol/L: 19.5085 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 645.803 | Positive charged surface: 360.606 | Negative charged surface: 281.217 | Volume: 371.125 |
Hydrophobic surface: 468.117 | Hydrophilic surface: 177.686 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |