Physical Properties | | | |
Molecular Weight: 531.597 g/mol | logS: -9.56428 | SlogP: 5.4207 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0773342 | Sterimol/B1: 2.50635 | Sterimol/B2: 2.85912 | Sterimol/B3: 5.86867 |
Sterimol/B4: 15.8013 | Sterimol/L: 19.2899 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 843.639 | Positive charged surface: 611.902 | Negative charged surface: 231.737 | Volume: 478.25 |
Hydrophobic surface: 696.669 | Hydrophilic surface: 146.97 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 9 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 3 | Oprea's lead like rule: 0 | |