Physical Properties | | | |
Molecular Weight: 421.504 g/mol | logS: -6.85183 | SlogP: 5.23649 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.046237 | Sterimol/B1: 2.44052 | Sterimol/B2: 3.87906 | Sterimol/B3: 5.26289 |
Sterimol/B4: 11.376 | Sterimol/L: 18.6821 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 734.61 | Positive charged surface: 431.518 | Negative charged surface: 303.092 | Volume: 410.625 |
Hydrophobic surface: 619.193 | Hydrophilic surface: 115.417 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |