Physical Properties | | | |
Molecular Weight: 402.454 g/mol | logS: -4.96556 | SlogP: 4.05292 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.05531 | Sterimol/B1: 2.4254 | Sterimol/B2: 3.15697 | Sterimol/B3: 4.84587 |
Sterimol/B4: 8.64712 | Sterimol/L: 17.7959 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 648.781 | Positive charged surface: 440.533 | Negative charged surface: 208.248 | Volume: 385.875 |
Hydrophobic surface: 530.419 | Hydrophilic surface: 118.362 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |