Physical Properties | | | |
Molecular Weight: 447.664 g/mol | logS: -5.2026 | SlogP: 3.05654 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.142966 | Sterimol/B1: 2.24434 | Sterimol/B2: 3.92867 | Sterimol/B3: 5.60316 |
Sterimol/B4: 10.3257 | Sterimol/L: 16.5421 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 752.093 | Positive charged surface: 503.294 | Negative charged surface: 248.799 | Volume: 464.875 |
Hydrophobic surface: 628.198 | Hydrophilic surface: 123.895 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |