Physical Properties | | | |
Molecular Weight: 397.427 g/mol | logS: -4.57099 | SlogP: 3.87692 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.118076 | Sterimol/B1: 3.98363 | Sterimol/B2: 4.59192 | Sterimol/B3: 5.81062 |
Sterimol/B4: 8.43267 | Sterimol/L: 17.5274 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 716.872 | Positive charged surface: 510.766 | Negative charged surface: 200.239 | Volume: 381 |
Hydrophobic surface: 642.325 | Hydrophilic surface: 74.547 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |