Physical Properties | | | |
Molecular Weight: 286.283 g/mol | logS: -2.25727 | SlogP: 1.7668 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0681458 | Sterimol/B1: 2.53389 | Sterimol/B2: 4.09258 | Sterimol/B3: 4.12069 |
Sterimol/B4: 6.76827 | Sterimol/L: 11.9808 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 440.478 | Positive charged surface: 217.42 | Negative charged surface: 219.17 | Volume: 224.125 |
Hydrophobic surface: 226.436 | Hydrophilic surface: 214.042 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |