Physical Properties | | | |
Molecular Weight: 408.498 g/mol | logS: -5.66825 | SlogP: 4.10687 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.079065 | Sterimol/B1: 3.88438 | Sterimol/B2: 5.07071 | Sterimol/B3: 6.35922 |
Sterimol/B4: 6.56451 | Sterimol/L: 18.7111 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 714.297 | Positive charged surface: 473.267 | Negative charged surface: 237.864 | Volume: 407.75 |
Hydrophobic surface: 563.395 | Hydrophilic surface: 150.902 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |