Physical Properties | | | |
Molecular Weight: 403.543 g/mol | logS: -3.44543 | SlogP: 1.6727 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.220686 | Sterimol/B1: 2.08399 | Sterimol/B2: 2.57441 | Sterimol/B3: 7.97464 |
Sterimol/B4: 10.9192 | Sterimol/L: 15.9273 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 682.599 | Positive charged surface: 575.244 | Negative charged surface: 107.354 | Volume: 410.5 |
Hydrophobic surface: 618.775 | Hydrophilic surface: 63.824 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |