Physical Properties | | | |
Molecular Weight: 402.467 g/mol | logS: -3.28918 | SlogP: 1.86767 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.37645 | Sterimol/B1: 4.19226 | Sterimol/B2: 4.56867 | Sterimol/B3: 5.53265 |
Sterimol/B4: 5.7914 | Sterimol/L: 13.7167 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 586.396 | Positive charged surface: 517.362 | Negative charged surface: 69.0345 | Volume: 386.75 |
Hydrophobic surface: 497.084 | Hydrophilic surface: 89.312 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |