Physical Properties | | | |
Molecular Weight: 403.478 g/mol | logS: -7.42484 | SlogP: 5.77788 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0447221 | Sterimol/B1: 2.14539 | Sterimol/B2: 3.26876 | Sterimol/B3: 5.12544 |
Sterimol/B4: 7.18523 | Sterimol/L: 21.238 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 699.293 | Positive charged surface: 414.556 | Negative charged surface: 279.199 | Volume: 395 |
Hydrophobic surface: 605.663 | Hydrophilic surface: 93.63 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |