Physical Properties | | | |
Molecular Weight: 429.493 g/mol | logS: -5.79796 | SlogP: 3.28984 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0408097 | Sterimol/B1: 2.33257 | Sterimol/B2: 2.84784 | Sterimol/B3: 5.37024 |
Sterimol/B4: 7.05003 | Sterimol/L: 21.5851 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 707.549 | Positive charged surface: 403.188 | Negative charged surface: 304.361 | Volume: 388.875 |
Hydrophobic surface: 538.994 | Hydrophilic surface: 168.555 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |