Physical Properties | | | |
Molecular Weight: 432.5 g/mol | logS: -4.72564 | SlogP: 4.8483 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.27944 | Sterimol/B1: 2.66688 | Sterimol/B2: 3.70242 | Sterimol/B3: 6.52248 |
Sterimol/B4: 9.40159 | Sterimol/L: 16.7315 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 701.02 | Positive charged surface: 391.816 | Negative charged surface: 309.204 | Volume: 401.125 |
Hydrophobic surface: 510.271 | Hydrophilic surface: 190.749 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |