Physical Properties | | | |
Molecular Weight: 402.447 g/mol | logS: -5.57352 | SlogP: 2.5154 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0706512 | Sterimol/B1: 2.18901 | Sterimol/B2: 3.18809 | Sterimol/B3: 4.97499 |
Sterimol/B4: 8.30863 | Sterimol/L: 19.5736 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 678.596 | Positive charged surface: 458.781 | Negative charged surface: 219.816 | Volume: 374.75 |
Hydrophobic surface: 473.501 | Hydrophilic surface: 205.095 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |