Physical Properties | | | |
Molecular Weight: 321.444 g/mol | logS: -3.79564 | SlogP: 3.9104 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.252805 | Sterimol/B1: 2.47971 | Sterimol/B2: 3.60182 | Sterimol/B3: 4.74933 |
Sterimol/B4: 9.90808 | Sterimol/L: 12.9984 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 560.504 | Positive charged surface: 374.726 | Negative charged surface: 185.778 | Volume: 333.5 |
Hydrophobic surface: 517.531 | Hydrophilic surface: 42.973 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 1 | Acid groups: 0 | Basic groups: 2 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |