Physical Properties | | | |
Molecular Weight: 426.513 g/mol | logS: -5.89485 | SlogP: 3.8374 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0663188 | Sterimol/B1: 2.13254 | Sterimol/B2: 4.15583 | Sterimol/B3: 7.40718 |
Sterimol/B4: 7.93899 | Sterimol/L: 19.1568 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 766.422 | Positive charged surface: 518.229 | Negative charged surface: 248.193 | Volume: 421.125 |
Hydrophobic surface: 598.53 | Hydrophilic surface: 167.892 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |