Physical Properties | | | |
Molecular Weight: 373.905 g/mol | logS: -3.10822 | SlogP: 1.561 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0685673 | Sterimol/B1: 2.49354 | Sterimol/B2: 3.57483 | Sterimol/B3: 5.25884 |
Sterimol/B4: 5.90831 | Sterimol/L: 18.2424 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 627.424 | Positive charged surface: 383.452 | Negative charged surface: 243.972 | Volume: 341.125 |
Hydrophobic surface: 498.502 | Hydrophilic surface: 128.922 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |