Physical Properties | | | |
Molecular Weight: 414.978 g/mol | logS: -4.214 | SlogP: 0.9241 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.091572 | Sterimol/B1: 3.57052 | Sterimol/B2: 4.74324 | Sterimol/B3: 5.16758 |
Sterimol/B4: 5.72019 | Sterimol/L: 18.1359 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 665.493 | Positive charged surface: 431.473 | Negative charged surface: 234.02 | Volume: 384.375 |
Hydrophobic surface: 524.469 | Hydrophilic surface: 141.024 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |