Physical Properties | | | |
Molecular Weight: 379.199 g/mol | logS: -4.92783 | SlogP: 3.4356 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.109428 | Sterimol/B1: 2.35047 | Sterimol/B2: 2.78796 | Sterimol/B3: 6.03094 |
Sterimol/B4: 6.3101 | Sterimol/L: 16.284 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 574.477 | Positive charged surface: 252.548 | Negative charged surface: 321.929 | Volume: 313.125 |
Hydrophobic surface: 405.857 | Hydrophilic surface: 168.62 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |