Physical Properties | | | |
Molecular Weight: 405.503 g/mol | logS: -6.21636 | SlogP: 2.7574 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0463166 | Sterimol/B1: 3.15609 | Sterimol/B2: 3.59448 | Sterimol/B3: 4.17439 |
Sterimol/B4: 8.45773 | Sterimol/L: 18.3645 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 647.939 | Positive charged surface: 355.536 | Negative charged surface: 292.403 | Volume: 353.75 |
Hydrophobic surface: 398.264 | Hydrophilic surface: 249.675 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |