Physical Properties | | | |
Molecular Weight: 396.539 g/mol | logS: -6.58026 | SlogP: 4.88822 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.067854 | Sterimol/B1: 2.99344 | Sterimol/B2: 3.0621 | Sterimol/B3: 5.02048 |
Sterimol/B4: 6.99693 | Sterimol/L: 19.9506 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 678.668 | Positive charged surface: 394.6 | Negative charged surface: 284.069 | Volume: 365.5 |
Hydrophobic surface: 520.98 | Hydrophilic surface: 157.688 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |