Physical Properties | | | |
Molecular Weight: 379.459 g/mol | logS: -6.63951 | SlogP: 5.42074 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0397858 | Sterimol/B1: 2.83271 | Sterimol/B2: 3.63425 | Sterimol/B3: 3.82094 |
Sterimol/B4: 8.84656 | Sterimol/L: 18.0373 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 644.941 | Positive charged surface: 342.142 | Negative charged surface: 296.576 | Volume: 352 |
Hydrophobic surface: 590.598 | Hydrophilic surface: 54.343 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |