Physical Properties | | | |
Molecular Weight: 418.558 g/mol | logS: -5.14106 | SlogP: 3.62162 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.12047 | Sterimol/B1: 3.19906 | Sterimol/B2: 4.09879 | Sterimol/B3: 5.61493 |
Sterimol/B4: 6.62386 | Sterimol/L: 18.6214 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 683.042 | Positive charged surface: 447.798 | Negative charged surface: 235.244 | Volume: 407.875 |
Hydrophobic surface: 549.851 | Hydrophilic surface: 133.191 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |