Physical Properties | | | |
Molecular Weight: 366.401 g/mol | logS: -4.33994 | SlogP: 0.0064 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.175451 | Sterimol/B1: 2.43457 | Sterimol/B2: 3.12428 | Sterimol/B3: 6.09616 |
Sterimol/B4: 7.90245 | Sterimol/L: 15.7413 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 630.11 | Positive charged surface: 397.488 | Negative charged surface: 232.622 | Volume: 341.875 |
Hydrophobic surface: 393.831 | Hydrophilic surface: 236.279 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |