Physical Properties | | | |
Molecular Weight: 386.536 g/mol | logS: -3.51069 | SlogP: 3.34816 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.080635 | Sterimol/B1: 2.25836 | Sterimol/B2: 4.4502 | Sterimol/B3: 5.39044 |
Sterimol/B4: 7.22715 | Sterimol/L: 20.6445 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 726.365 | Positive charged surface: 541.15 | Negative charged surface: 185.215 | Volume: 407.125 |
Hydrophobic surface: 666.304 | Hydrophilic surface: 60.061 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |