Physical Properties | | | |
Molecular Weight: 396.486 g/mol | logS: -3.99216 | SlogP: 2.10767 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0603509 | Sterimol/B1: 2.56724 | Sterimol/B2: 3.74032 | Sterimol/B3: 3.77357 |
Sterimol/B4: 7.85049 | Sterimol/L: 18.7274 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 677.282 | Positive charged surface: 455.144 | Negative charged surface: 218.158 | Volume: 392.625 |
Hydrophobic surface: 586.02 | Hydrophilic surface: 91.262 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |