Physical Properties | | | |
Molecular Weight: 415.494 g/mol | logS: -4.99595 | SlogP: 2.5678 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0560824 | Sterimol/B1: 2.26311 | Sterimol/B2: 3.44358 | Sterimol/B3: 5.48517 |
Sterimol/B4: 8.27622 | Sterimol/L: 20.1688 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 685.576 | Positive charged surface: 304.048 | Negative charged surface: 381.528 | Volume: 358.75 |
Hydrophobic surface: 501.524 | Hydrophilic surface: 184.052 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |