Physical Properties | | | |
Molecular Weight: 414.442 g/mol | logS: -4.82493 | SlogP: 1.78492 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.141372 | Sterimol/B1: 2.44841 | Sterimol/B2: 3.70736 | Sterimol/B3: 4.72204 |
Sterimol/B4: 10.9857 | Sterimol/L: 15.4539 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 647.424 | Positive charged surface: 374.954 | Negative charged surface: 272.471 | Volume: 355.375 |
Hydrophobic surface: 414.55 | Hydrophilic surface: 232.874 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |