Physical Properties | | | |
Molecular Weight: 375.452 g/mol | logS: -6.55229 | SlogP: 4.85032 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0255555 | Sterimol/B1: 2.09183 | Sterimol/B2: 2.56422 | Sterimol/B3: 3.7887 |
Sterimol/B4: 9.64681 | Sterimol/L: 17.7312 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 628.114 | Positive charged surface: 325.277 | Negative charged surface: 297.16 | Volume: 350.75 |
Hydrophobic surface: 556.401 | Hydrophilic surface: 71.713 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |