Physical Properties | | | |
Molecular Weight: 411.523 g/mol | logS: -3.68731 | SlogP: 1.8258 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0874637 | Sterimol/B1: 2.18839 | Sterimol/B2: 4.4434 | Sterimol/B3: 4.96257 |
Sterimol/B4: 10.6591 | Sterimol/L: 17.2094 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 711.726 | Positive charged surface: 454.983 | Negative charged surface: 256.743 | Volume: 382.125 |
Hydrophobic surface: 481.211 | Hydrophilic surface: 230.515 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |