Physical Properties | | | |
Molecular Weight: 410.514 g/mol | logS: -5.03833 | SlogP: 3.3172 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0457949 | Sterimol/B1: 3.02502 | Sterimol/B2: 3.67757 | Sterimol/B3: 4.33453 |
Sterimol/B4: 6.72801 | Sterimol/L: 20.2318 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 694.621 | Positive charged surface: 511.681 | Negative charged surface: 182.94 | Volume: 398.5 |
Hydrophobic surface: 577.903 | Hydrophilic surface: 116.718 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |