Physical Properties | | | |
Molecular Weight: 378.331 g/mol | logS: -4.57595 | SlogP: 1.8851 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.00653423 | Sterimol/B1: 2.68213 | Sterimol/B2: 2.72912 | Sterimol/B3: 3.7726 |
Sterimol/B4: 4.32452 | Sterimol/L: 23.4141 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 643.547 | Positive charged surface: 385.782 | Negative charged surface: 257.765 | Volume: 325.375 |
Hydrophobic surface: 498.743 | Hydrophilic surface: 144.804 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |