Physical Properties | | | |
Molecular Weight: 376.403 g/mol | logS: -4.15506 | SlogP: 2.6288 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0513108 | Sterimol/B1: 2.40882 | Sterimol/B2: 4.84967 | Sterimol/B3: 6.0025 |
Sterimol/B4: 6.10909 | Sterimol/L: 18.3373 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 641.267 | Positive charged surface: 408.903 | Negative charged surface: 232.363 | Volume: 347.125 |
Hydrophobic surface: 581.422 | Hydrophilic surface: 59.845 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |