Physical Properties | | | |
Molecular Weight: 376.452 g/mol | logS: -4.52458 | SlogP: 2.58924 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.145112 | Sterimol/B1: 1.98101 | Sterimol/B2: 4.89618 | Sterimol/B3: 5.04957 |
Sterimol/B4: 7.07374 | Sterimol/L: 16.1382 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 617.983 | Positive charged surface: 352.64 | Negative charged surface: 265.344 | Volume: 341.625 |
Hydrophobic surface: 530.591 | Hydrophilic surface: 87.392 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |