Physical Properties | | | |
Molecular Weight: 420.961 g/mol | logS: -4.96415 | SlogP: 3.87717 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0335807 | Sterimol/B1: 3.26878 | Sterimol/B2: 3.63471 | Sterimol/B3: 3.72926 |
Sterimol/B4: 6.62349 | Sterimol/L: 20.8739 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 674.772 | Positive charged surface: 393.061 | Negative charged surface: 281.71 | Volume: 383.875 |
Hydrophobic surface: 586.597 | Hydrophilic surface: 88.175 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |