Physical Properties | | | |
Molecular Weight: 387.287 g/mol | logS: -4.89748 | SlogP: 3.80442 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0806104 | Sterimol/B1: 2.28834 | Sterimol/B2: 2.54986 | Sterimol/B3: 5.48114 |
Sterimol/B4: 8.40189 | Sterimol/L: 15.8422 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 596.943 | Positive charged surface: 299.214 | Negative charged surface: 297.729 | Volume: 325.375 |
Hydrophobic surface: 519.804 | Hydrophilic surface: 77.139 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |