Physical Properties | | | |
Molecular Weight: 400.478 g/mol | logS: -6.70674 | SlogP: 4.38914 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0255968 | Sterimol/B1: 2.22144 | Sterimol/B2: 3.60604 | Sterimol/B3: 3.7507 |
Sterimol/B4: 9.55962 | Sterimol/L: 21.8724 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 726.956 | Positive charged surface: 457.79 | Negative charged surface: 269.166 | Volume: 394.25 |
Hydrophobic surface: 643.073 | Hydrophilic surface: 83.883 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |