Physical Properties | | | |
Molecular Weight: 287.326 g/mol | logS: -4.64302 | SlogP: 3.5288 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0492813 | Sterimol/B1: 2.73578 | Sterimol/B2: 3.15761 | Sterimol/B3: 4.42577 |
Sterimol/B4: 5.53429 | Sterimol/L: 15.3202 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 504.079 | Positive charged surface: 326.017 | Negative charged surface: 178.062 | Volume: 273.875 |
Hydrophobic surface: 399.775 | Hydrophilic surface: 104.304 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |