Physical Properties | | | |
Molecular Weight: 398.487 g/mol | logS: -4.35179 | SlogP: 2.32644 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0996921 | Sterimol/B1: 2.51452 | Sterimol/B2: 2.57084 | Sterimol/B3: 6.31365 |
Sterimol/B4: 6.56193 | Sterimol/L: 18.9606 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 630.559 | Positive charged surface: 376.036 | Negative charged surface: 248.038 | Volume: 359.875 |
Hydrophobic surface: 502.943 | Hydrophilic surface: 127.616 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |