Physical Properties | | | |
Molecular Weight: 403.91 g/mol | logS: -5.64016 | SlogP: 3.93182 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0514741 | Sterimol/B1: 2.1895 | Sterimol/B2: 3.50815 | Sterimol/B3: 4.61942 |
Sterimol/B4: 8.71074 | Sterimol/L: 20.1176 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 693.275 | Positive charged surface: 401.19 | Negative charged surface: 292.085 | Volume: 384 |
Hydrophobic surface: 574.481 | Hydrophilic surface: 118.794 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |