Physical Properties | | | |
Molecular Weight: 407.507 g/mol | logS: -4.74486 | SlogP: 3.7344 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0339684 | Sterimol/B1: 2.56066 | Sterimol/B2: 3.72349 | Sterimol/B3: 4.08415 |
Sterimol/B4: 10.4664 | Sterimol/L: 19.9935 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 767.818 | Positive charged surface: 574.188 | Negative charged surface: 193.63 | Volume: 409.25 |
Hydrophobic surface: 590.395 | Hydrophilic surface: 177.423 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |