Physical Properties | | | |
Molecular Weight: 374.396 g/mol | logS: -4.328 | SlogP: 3.9141 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.113801 | Sterimol/B1: 3.22469 | Sterimol/B2: 3.31121 | Sterimol/B3: 4.14174 |
Sterimol/B4: 8.68339 | Sterimol/L: 13.5306 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 576.488 | Positive charged surface: 377.399 | Negative charged surface: 193.995 | Volume: 343.75 |
Hydrophobic surface: 424.693 | Hydrophilic surface: 151.795 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |