Physical Properties | | | |
Molecular Weight: 414.554 g/mol | logS: -7.35853 | SlogP: 4.66212 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0348734 | Sterimol/B1: 2.2869 | Sterimol/B2: 3.75575 | Sterimol/B3: 4.56151 |
Sterimol/B4: 8.84777 | Sterimol/L: 20.9497 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 732.866 | Positive charged surface: 428.438 | Negative charged surface: 304.428 | Volume: 386.625 |
Hydrophobic surface: 569.743 | Hydrophilic surface: 163.123 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |