Physical Properties | | | |
Molecular Weight: 412.667 g/mol | logS: -5.49702 | SlogP: 3.9378 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0389984 | Sterimol/B1: 2.16031 | Sterimol/B2: 4.19747 | Sterimol/B3: 5.25169 |
Sterimol/B4: 5.72355 | Sterimol/L: 19.3558 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 632.878 | Positive charged surface: 286.521 | Negative charged surface: 346.357 | Volume: 330.125 |
Hydrophobic surface: 495.995 | Hydrophilic surface: 136.883 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |