Physical Properties | | | |
Molecular Weight: 401.314 g/mol | logS: -4.74252 | SlogP: 3.21617 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0497217 | Sterimol/B1: 2.06631 | Sterimol/B2: 3.6146 | Sterimol/B3: 4.4762 |
Sterimol/B4: 7.41895 | Sterimol/L: 20.1016 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 645.47 | Positive charged surface: 328.881 | Negative charged surface: 316.589 | Volume: 343.5 |
Hydrophobic surface: 546.399 | Hydrophilic surface: 99.071 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |