Physical Properties | | | |
Molecular Weight: 417.482 g/mol | logS: -3.86033 | SlogP: 1.4227 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0861482 | Sterimol/B1: 2.28139 | Sterimol/B2: 4.00125 | Sterimol/B3: 5.45692 |
Sterimol/B4: 7.39161 | Sterimol/L: 17.7503 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 676.265 | Positive charged surface: 380.073 | Negative charged surface: 296.192 | Volume: 375.25 |
Hydrophobic surface: 520.043 | Hydrophilic surface: 156.222 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |