Physical Properties | | | |
Molecular Weight: 396.467 g/mol | logS: -5.14267 | SlogP: 3.7726 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0657306 | Sterimol/B1: 2.36825 | Sterimol/B2: 3.26073 | Sterimol/B3: 4.92227 |
Sterimol/B4: 7.22912 | Sterimol/L: 20.1224 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 638.737 | Positive charged surface: 374.356 | Negative charged surface: 264.381 | Volume: 363.375 |
Hydrophobic surface: 537.413 | Hydrophilic surface: 101.324 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |