Physical Properties | | | |
Molecular Weight: 371.389 g/mol | logS: -4.99628 | SlogP: 2.97422 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0250982 | Sterimol/B1: 2.55927 | Sterimol/B2: 4.30237 | Sterimol/B3: 5.01082 |
Sterimol/B4: 6.47255 | Sterimol/L: 19.7696 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 680.522 | Positive charged surface: 454.414 | Negative charged surface: 226.108 | Volume: 350.75 |
Hydrophobic surface: 534.682 | Hydrophilic surface: 145.84 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |