Physical Properties | | | |
Molecular Weight: 481.953 g/mol | logS: -5.49406 | SlogP: 3.5699 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0367935 | Sterimol/B1: 2.25152 | Sterimol/B2: 3.74157 | Sterimol/B3: 6.63998 |
Sterimol/B4: 6.69301 | Sterimol/L: 21.5228 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 745.47 | Positive charged surface: 477.479 | Negative charged surface: 267.99 | Volume: 418 |
Hydrophobic surface: 599.016 | Hydrophilic surface: 146.454 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |